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Intercept has a research pipeline based on FXR, a regulator of bile acid pathways in the hepatic system. The lead compound, obeticholic acid OCA , is an analog of the bile acid CDCA, and as such can take a role in the FXR pathways and receptors implicated in chronic liver disease.
Treating liver disease through the FXR biology has direct applications for PBC, and is showing promise treating complications from NASH. The effect on the stock is still felt, and ICPT remains at its week low point.
In reaction, in December of , Intercept announced major changes in top-level management, as CEO and President Mark Pruzanski announced he's stepping down effective January 1 of this year.
Pruzanski's dedication to transform the liver space is still strong, and that he will continue to guide ICPT's progress as an advisor and Board member.
Additionally, we have had the pleasure of working closely with Jerry Durso and believe that he will transform the company and lead ICPT's success in growing the PBC market and the path to potential approval and commercial launch of OCA in NASH.
ICPT's Moderate Buy consensus rating is based on 17 reviews, including 8 Buys and 9 Holds. See ICPT stock analysis on TipRanks Gilead Sciences GILD Gilead has had a year like a firework — fast up and fast down.
By November, however, even though remdesivir had been approved, the World Health Organization WHO was recommending against its use, and the COVID vaccines now on the market have made remdesivir irrelevant to the pandemic.
The company has been working, in conjunction with Galapagos GLPG , on development of filgotinib as a treatment for rheumatoid arthritis. While the drug received EU and Japanese approval in September , the FDA has withheld approval and Gilead announced in December that it was suspending US development efforts on the drug.
Among the bulls is Oppenheimer analyst Hartaj Singh, who gives GILD shares an Outperform i. Looking at the consensus breakdown, opinions from other analysts are more spread out.
Disclaimer: The opinions expressed in this article are solely those of the featured analysts. The content is intended to be used for informational purposes only.
It is very important to do your own analysis before making any investment. A Democrat victory in both Georgia runoff elections could have huge implications for tax and spending policy, the shape of the coronavirus recovery and the stock market outlook.
Speculation has mounted over the reason behind his disappearance, which some publications have connected to a late October speech in which he appeared to call for a reform of China's banking system.
Bloomberg -- U. To combat the economic fallout from the Covid pandemic, the central bank cut rates to almost zero. The equity gauge finished the year at an all-time high of 3, Pessimism over tech giants such as Apple Inc.
For the coming year, Wien and Zidle expect the Fed and the Treasury will continue their accommodative policies to bolster the economy.
Faster inflation, while still modest, is set to fuel gains in gold and boost the allure of cryptocurrencies, they say.
The duo also project a reversal in the U. Below are his other calls for The Fed extends the duration of bond purchases in order to prevent higher rates at the long end of the curveFormer President Donald Trump starts his own television network and plans his campaignChinese shares to lead emerging markets as President Joe Biden begins to restore trade relationships with ChinaCyclical shares lead defensives, small-caps beat large-caps.
Both energy bonds and stocks rally Updates with more predictions starting in seventh paragraph For more articles like this, please visit us at bloomberg.
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